In these cases a small amount of additional standard damage is applied to the target instead. Most sources of Fatigue damage make exceptions for robots and the Courier, as neither should ever be rendered fully unconscious. All shotguns chambered for the 12 gauge shell can also cause Fatigue damage if loaded with 12 gauge bean bag ammunition. Only five weapons inherently cause Fatigue damage: boxing gloves, boxing tape, cattle prod, flash bangs, and Golden Gloves.
In Fallout: New Vegas, the number of sources which induce Fatigue damage are limited. Main article: Fatigue (Fallout: New Vegas)